May 2006
Volume 47, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2006
Electrical Stimulation of Extraocular Muscle of Rabbit
Author Affiliations & Notes
  • U. Park
    Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Republic of Korea
    Seoul Artificial Eye Center, Seoul National University Hospital Clinical Research Institute, Seoul, Republic of Korea
  • S.–J. Kim
    Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Republic of Korea
    Seoul Artificial Eye Center, Seoul National University Hospital Clinical Research Institute, Seoul, Republic of Korea
  • Y.S. Yu
    Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Republic of Korea
    Seoul Artificial Eye Center, Seoul National University Hospital Clinical Research Institute, Seoul, Republic of Korea
  • Footnotes
    Commercial Relationships  U. Park, None; S. Kim, None; Y.S. Yu, None.
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science May 2006, Vol.47, 5061. doi:
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      U. Park, S.–J. Kim, Y.S. Yu; Electrical Stimulation of Extraocular Muscle of Rabbit . Invest. Ophthalmol. Vis. Sci. 2006;47(13):5061.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : To verify the contraction of extraocular muscle under electrical stimulation and identify the appropriate stimulation condition to contract the muscle maximally.

Methods: : About 10mm–long anterior part of superior rectus muscle was exposed after removal of upper lid in rabbit. Platinum double–rod bipolar electrode was inserted under the superior rectus and electrical stimuli with various waveforms, polarity and levels of voltage, pulse duration, interval were delivered.

Results: : With cathodic monophasic stimulation, most intense contraction was observed. Muscle maintained contraction as long as the current flows, independent of pulse duration or interval. With stronger than 2.0V stimulation, gross contraction occurred and the length of contraction was in proportion to the level of voltage, but in inverse proportion to the distance between the electrodes. Maximal length of contraction was 1.0mm with 5.0V stimulation.

Conclusions: : Extraocular muscle of rabbit was verified to contract under electrical stimulation. However, further investigation to provoke stronger contraction enough to rotate an eyeball is needed.

Keywords: eye movements 
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