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S. Ishiko, E. Sato, H. Kagokawa, J. Takahashi, M. Takeda, A. Takahashi, Y. Kato, A. Yoshida; Preferred Retinal Locus and Visual Acuity in Eyes With Macular Disease . Invest. Ophthalmol. Vis. Sci. 2006;47(13):5203.
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Several reports have been published on the correlation between visual acuity (VA) and foveal thickness after macular surgery. However, because the preferred retinal locus (PRL) at the fovea often is affected in macular disease, the area with pathologic changes that is evaluated and the lesions that produce the VA changes might differ. To clarify the characteristics of the PRL in macular disease, we studied the relation between the PRL and the VA in eyes with several macular diseases.
Of the 2,136 eyes that underwent a PRL evaluation using scanning laser ophthalmoscope microperimetry at Asahikawa Medical College from 1999 to 2005, the following were included: 51 eyes had a preretinal membrane (PRM); 56 highly myopic eyes, chorioretinal atrophy (HMC); 48 highly myopic eyes, no chorioretinal atrophy (HMN); 112 eyes, diabetic macular edema (DME); 52 eyes, branch retinal vein occlusion (BRVO); and 156 eyes age–related macular degeneration (AMD). The PRLs were classified into 2 groups: a functioning PRL at the fovea and a PRL not at the fovea. We studied the relation between PRL and VA in each disease.
In most eyes with PRM and HMN, the PRLs were at the fovea regardless of the VA. In all eyes with DME and VA ≥0.3, the PRL was at the fovea, and in eyes with DME and VA <0.1, the PRL was not at the fovea in 76.9%. In eyes with HMC, BRVO, and AMD and VA <0.1, the PRL was not at the fovea in more than 90%, and the PRL in some eyes in these groups was not at the fovea despite VA ≥0.3.
Depending on the macular disease, the PRL remained at the fovea or was easily moved from the fovea. Considering the characteristics of the PRL in each disease and evaluating the PRL are essential when studying the correlation between VA and pathologic foveal changes such as foveal thickness in eyes with macular disease.
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