May 2006
Volume 47, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2006
Early Vitrectomy for ROP
Author Affiliations & Notes
  • F. Molle
    Ophthalmology, Catholic University, Rome, Italy
  • D. Lepore
    Ophthalmology, Catholic University, Rome, Italy
  • M.M. Pagliara
    Ophthalmology, Catholic University, Rome, Italy
  • A. Baldascino
    Ophthalmology, Catholic University, Rome, Italy
  • R. De Santis
    Ophthalmology, Catholic University, Rome, Italy
  • G. D'Amico
    Ophthalmology, Catholic University, Rome, Italy
  • C. Angora
    Ophthalmology, Catholic University, Rome, Italy
  • L. Orazi
    Ophthalmology, Catholic University, Rome, Italy
  • M. Laguardia
    Ophthalmology, Catholic University, Rome, Italy
  • E. Balestrazzi
    Ophthalmology, Catholic University, Rome, Italy
  • Footnotes
    Commercial Relationships  F. Molle, None; D. Lepore, None; M.M. Pagliara, None; A. Baldascino, None; R. De Santis, None; G. D'Amico, None; C. Angora, None; L. Orazi, None; M. Laguardia, None; E. Balestrazzi, None.
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science May 2006, Vol.47, 5312. doi:
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      F. Molle, D. Lepore, M.M. Pagliara, A. Baldascino, R. De Santis, G. D'Amico, C. Angora, L. Orazi, M. Laguardia, E. Balestrazzi; Early Vitrectomy for ROP . Invest. Ophthalmol. Vis. Sci. 2006;47(13):5312.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : according to ET ROP study 19,9% of ROP progrees to stage 4 and 5 despite avacsular retina photoablation. The purpose of this study is to evaluate if early vitrectomy could represent a useful treatment for ROP in case of laser failure.

Methods: : from jan 1st 2004 to june 30 2005 14 inborn preterm (28eyes), with mean gestational age (GA) 26,14 weeks (range 24–30wks) and a mean birth weight (BW) 739,29gr (460–1250gr) were treated with laser. Three babies (6eyes) progressed to stage 5 and 2 eyes (1 baby) to stage 4b despite laser. Two port lens–sparing vitrectomy (LSV) was performed in these cases at a mean postconceptional age of 38,16 weeks (range 33,1–42,0wks).

Results: : structural outcomes at six–month follow–up are presented here. In one baby (2 eyes) partial retinal reattachment was achieved. Two eyes from 1 baby showed a massive retinal degeneration despite partial reattachment. Resumption of preretinal fibrous proliferation requiring reintervention, was observed in 4 eyes.

Conclusions: : From literature LSV is the only therapy porposed for ROP after laser failure. In our experience only 2 on 8 eyes showed retinal stabilisation and RLF prevention. Although some light perception was clearly still present in these eyes LSV usefulness remains questionable.

Keywords: retinopathy of prematurity 
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