Abstract
Purpose: :
To assess the visual acuity (VA) of eyes successfully treated with three–port lens–sparing vitrectomy (LSV) for stage 4 retinopathy of prematurity (ROP) in a consecutive, single surgeon study.
Methods: :
Of 102 consecutive eyes achieving at least posterior pole reattachment after LSV, 30 eyes of 26 patients, 14 stage 4A and 16 stage 4B, were tested for VA outcomes by Teller or Allen acuity measurements and were subsequently converted to logarithm of the minimum angle of resolution (LogMAR).
Results: :
Seventy–two eyes were unable to be tested due to either inability to perform testing (age or neurologic sequelae related to prematurity) or loss of follow–up. Mean LogMAR VA for the stage 4A and stage 4B groups was 0.51 ± 0.10 (Snellen approximate 20/62) and 1.03 ± 0.19 (Snellen approximate 20/200), respectively. After differences in birthweight, gestational age, age and mode of VA testing, and zone 1 disease between stage 4A and stage 4B groups were controlled for, logistic regression analysis demonstrated a statistically significant difference in mean LogMAR VA between the two groups (odds ratio [OR]: 0.39; 95% confidence interval [CI]: 0.24–0.64; P = .001).
Conclusions: :
Among eyes tested after successful three–port LSV, some eyes treated prior to macular detachment may be associated with a more favorable outcome and improved maintenance of functional visual acuity.
Keywords: retinopathy of prematurity • vitreoretinal surgery • clinical (human) or epidemiologic studies: outcomes/complications