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R.W. Essex, J. Wong, A. Tufail, A. Bird, J. Dowler; Punctate Inner Choroidopathy and Choroidal Neovascularization – Natural History . Invest. Ophthalmol. Vis. Sci. 2006;47(13):5637.
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To describe the clinical features and visual outcomes of punctate inner choroidopathy (PIC) related choroidal neovascularisation (CNV).
Retrospective chart review. All patients seen in the retinal clinics at Moorfields Eye Hospital identified through an electronic patient record and also through personal observation over a 5 year period with the diagnosois of PIC complicated by CNV were eligible for inclusion in the study. Eyes which received any treatment for the CNV were excluded. The charts were reviewed when available. Baseline ocular and demographic data were collected. The visual outcomes were sought as was the behaviour of the fellow eye.
Preliminary data collection has identified 38 patients with untreated PIC related CNV. Median age was 29 years. 92% were female and 95% myopic. 45% had unilateral punctate choroidal lesions at presentation and 55% bilateral. CNV was present on presentation in 89% of study eyes, 52% of which were subfoveal. CNV was present in 15% of fellow eyes at presentation and eventually developed in another 28%. Median follow is 49 months. Median baseline vision was 6/18 (range 6/6 – HM). Median final visual acuity was 6/24 (range 6/6 – CF).
The natural history of PIC related CNV is less aggressive than for CNV related to age–related macular degeneration.
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