Abstract
Purpose: :
Humphrey Matrix is a second–generation perimeter of frequency doubling technology (FDT). Humphrey Matrix is able to present a smaller size target (2×2 degrees) compared with the original FDT, and a high–resolution analysis can be obtained. Although FDT was originally developed for the diagnosis of glaucoma, Chris Johnson indicates that Humphrey Matrix is a promising tool for the detection of macular diseases. We studied the performance of Humphrey Matrix in the detection of macular disease.
Methods: :
Twenty–four eyes of 24 patients with macular disease (mean age: 61.0±12.3 year) and 12 eyes of 12 normal persons were studied (mean age: 58.8±10.1 year). The macular diseases were preretinal membrane in 11 eyes, macular hole in 2 eyes, macular degeneration in 3 eyes, detachment of retinal pigment epithelium in 2 eyes, age related macular degeneration in 3 eyes, and central serous retinochoroidopathy in 2 eyes. The 10–2 program of Humphrey Field Analyzer (HFA) and Humphrey Matrix were performed on each subject.
Results: :
HFA and Humphrey Matrix detected macular disease at sensitivity of 67% and 88%, and specificity of 100% and 100%, respectively. All 16 patients who had abnormal HFA results also showed abnormal results on Humphrey Matrix, whereas 5 of 8 patients who had normal HFA results had abnormal Humphrey Matrix results. The correlation between MD determined by HFA (x) and that determined by Humphrey Matrix (y) is shown as y=0.95x–3.00 (r=0.79, p<0.0001), and the correlation of PSD was y=0.40x+3.20 (r=0.74,p<0.0001).
Conclusions: :
Visual field indices (MD and PSD) obtained by HFA and Humphrey Matrix correlate significantly, and Humphrey Matrix is more sensitive than HFA in the detection of macular diseases.
Keywords: visual fields • macula/fovea • perimetry