May 2005
Volume 46, Issue 13
ARVO Annual Meeting Abstract  |   May 2005
Efficacy of Multiple Selective Laser Trabeculoplasty Treatments in Open Angle Glaucoma
Author Affiliations & Notes
  • J.S. de Leon
    Ophthalmology, Massachusetts Eye and Ear Infirmary, Boston, MA
  • J.J. Dagianis
    Ophthalmology, Nashua Eye Associates, Nashua, NH
  • M.A. Latina
    Ophthalmology, Tufts University, Medford, MA
  • Footnotes
    Commercial Relationships  J.S. de Leon, None; J.J. Dagianis, None; M.A. Latina, Lumenis, Inc C, P.
  • Footnotes
    Support  None.
Investigative Ophthalmology & Visual Science May 2005, Vol.46, 108. doi:
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    • Get Citation

      J.S. de Leon, J.J. Dagianis, M.A. Latina; Efficacy of Multiple Selective Laser Trabeculoplasty Treatments in Open Angle Glaucoma . Invest. Ophthalmol. Vis. Sci. 2005;46(13):108.

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      © ARVO (1962-2015); The Authors (2016-present)

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To determine the magnitude of IOP reduction, responserate (RR) and time between multiple SLT treatments in eyes withopen angle glaucoma.


This is a retrospective study of 49 glaucomatous eyes(2 OHT, 2 Pigmentary, 1 PXFG, and 44 POAG) of 39 patients. 5eyes had prior ALT, 8 eyes were pseudophakic, 37 eyes were onand 12 eyes were off glaucoma meds. SLT 1 & 2 treatmentswere 1800 and 180–3600 for SLT 3. A successful responsewas an IOP reduction >3 mmHg from baseline at 6+1 month postSLT. A minimum of 6 month’s f/u up was required for studyinclusion.


Mean f/u up time for all eyes were 23.3+8.6 mos (range:6– 43). Mean baseline IOP (mm Hg) was 22.5+5.2 with amean of 1.3 glaucoma meds before SLT 1. Mean IOP reductionsfrom baseline, and RR at 6 mos after treatment were: SLT 1(n=49):3.3+5, RR 51%, SLT 2(n=45): 4.2+5.7, RR 58%, SLT 3(n=6): 10.6+7.2,RR 100%. Eyes were divided based on initial baseline IOP>21or IOP<21. IOP reduction and RR’s were compared foreach SLT treatment.


IOP Reduction: 

Response Rates:



SLT 2 was done after a mean of 12.7+7.3 mos after SLT 1. SLT3 was done after a mean of 15+5 mos after the SLT 2. There wasno significant change in the no. of glaucoma meds during thestudy. In this heterogeneous group of eyes followedup for an average of 2 years, the mean time between SLT treatmentswas 12–15 months. Eyes with baseline IOP's>21 wereassociated with a greater magnitude of IOP reduction and responserate for each SLT treatment. Although the sample size for SLT3 was small, the data is suggestive that repeat SLT’swould have a greater likelihood of success in eyes with baselineIOP’s >21.


Keywords: laser • trabecular meshwork • intraocular pressure 

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