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A.M. Bovell, K.F. Damji, W.G. Hodge, W. Rock, R. Buhrmann, Y. Pan; Selective Laser Trabeculoplasty (SLT) vs. Argon Laser Trabeculoplasty (ALT) Response in Phakic and Pseudophakic Patients . Invest. Ophthalmol. Vis. Sci. 2005;46(13):112.
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As part of a randomized clinical trial comparing the efficacy and safety of SLT vs. ALT, we compared the IOP lowering response of SLT vs. ALT in phakic and pseudophakic eyes.
Patients with open angle glaucoma were randomized to treatment with SLT or ALT, using standard treatment parameters. Primary outcome was decrease in IOP from pretreatment baseline compared to 1 year post treatment.
Baseline IOP in the phakic and pseudophakic groups was comparable for both the SLT and ALT groups. The mean IOP at 1 year was not statistically different in phakic vs. pseudophakic patients, treated with either SLT or ALT (see table).
SLT and ALT treatment produce equivalent IOP lowering in phakic patients and similar IOP lowering in pseudophakic patients, at one year. A larger sample size is needed to establish equivalence in pseudophakes.
Acknowledgement: Lumenis Inc. provided financial support for our randomized trial comparing SLT to ALT
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