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J.L. S. See, P.T. K. Chew, W.P. Nolan, C. Zheng, R. Sunita, S. Smith, D. Friedman, T. Aung; Effect of Laser Peripheral Iridotomy on Angle Configuration in Eyes With Angle Closure: An Evaluation by the Anterior Segment OCT . Invest. Ophthalmol. Vis. Sci. 2005;46(13):139.
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© ARVO (1962-2015); The Authors (2016-present)
Purpose: To evaluate the effect of laser peripheral iridotomy on angle configuration in eyes with angle closure, using the anterior segment optical coherence tomograph (AS–OCT). Methods: Patients attending the glaucoma service at the National University Hospital, Singapore were recruited into this study. Those identified to have angle closure underwent imaging with the AS–OCT (Carl Zeiss Meditec, Inc, Dublin, CA, USA) before and after laser iridotomy. Images of the nasal, temporal and inferior quadrants were acquired in all eyes. The AS–OCT images of the right eyes obtained under dark conditions were analysed for angle opening distance at 500µm (AOD500), area of recessed angle (ARA500) and trabecular–iris space area (TISA). Results: Ten patients were analysed in this preliminary study, including 4 men and 6 women. The mean age was 62.4 years ± 8.3. After laser iridotomy, there was a significant increase in AOD500 in the nasal, temporal and inferior angles (p=0.03, p=0.02, p=0.01 respectively). However, ARA500 did not show a significant change post–laser iridotomy and TISA showed a significant increase only in the temporal angles. Conclusions: In eyes with angle closure, the angle opening distance (AOD500) was found to increase significantly after laser iridotomy. The AS–OCT is a promising imaging device that allows assessment of changes in angle configuration after laser iridotomy in eyes with angle closure.
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