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G. Alvarez–Rivera, H. Flores–Orta, R. Flores–Orta, D. Mozas–Dávila, J. Villar–Kuri, M. De Regil, M. Ambesi–Impiombato, N. Ibarra–Ponce, H. Quiroz–Mercado; Visual Results and Follow Up of Patients With Age Related Macular Degeneration Operated of Phacoemulsification and Intraocular Lens Implantation With and Without Triamcinolone Acetonide . Invest. Ophthalmol. Vis. Sci. 2005;46(13):213.
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Purpose:Age–related macular degeneration (AMD) and cataract are strongly related to age, and each has a number of identified risk factors. Cataract surgery is currently one of the most frequently performed and successful surgical procedures, the association between cataract surgery and progression AMD is not clear. However lens opacity may preclude accurate assessment of maculopathy and be an obstacle for laser treatment. Triamcinolone acetonide (KENALOGTM) is a synthetic corticosteroid and is given by injection in many situations where a lasting corticosteroid effect is required. Our purpose is to compare the visual results and follow up of patients with AMD who underwent cataract surgery with and without KENALOGTM. Methods: Patients with diagnostic of AMD and cataract were evaluated by clinical, angiography and OCT test previous to surgical event. The cataract surgery technique performed was an uncomplicated phacoemulsification and intraocular lens implantation, and in randomized selected eye we applied intravitreal triamcinolone acetonide (0.4 mg) via pars plana. The postoperative follow up include visual capacity, tonometry, Amsler grid, angiography and OCT test at 1, 3 and 6 months. Results:We report 10 patients, 7 women and 3 men, average age 71 years old, 14 eyes evaluated divided in 10 cases and 4 controls, the average initial visual acuity was 20/160. At first month posterior cataract surgery, no changes of intraocular pressure was observe, the average visual acuity improve to 20/80 and the rest remain unchanged. At third month one patient who underwent cataract surgery without KENALOGTM decrease visual acuity by active membrane. Conclusions: Cataract surgery may accelerate progression of AMD; KENALOGTM may inhibit release of inflammatory mediators and stabilize AMD. This is a preliminary report that could lead to further investigation
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