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J. Wagner, C. Simader, S. Michels, U. Schmidt–Erfurth; Correlation of Functional Mapping and Optical Coherence Tomography (OCT) in Full–Thickness Macular Holes and Partial Thickness Macular Holes . Invest. Ophthalmol. Vis. Sci. 2005;46(13):260.
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© ARVO (1962-2015); The Authors (2016-present)
Purpose: To correlate functional macular mapping using the Nidek MP1 microperimetry system with optical coherence tomography (Stratus OCT) in full–thickness macular holes stage II–IV and partial–thickness macular holes. Methods: Nidek MP1 functional macular mapping and high resolution radial scans using Stratus OCT were used to compare functional and anatomic characteristics in full–thickness and partial–thickness macular holes. Results: Functional mapping in full thickness macular holes > 300µm characteristically showed a central absolute scotoma. Smaller full thickness holes frequently demonstrate no absolute scotoma. All full–thickness macular holes are associated with a relative scotoma with decreasing intensity towards the periphery of the defect. The perifoveal increase in retinal thickness as documented by Stratus OCT typically extends beyond the clinically appreciated halo surrounding a full thickness macular hole. However, the circular relative scotoma, seen in functional macular mapping, correlates well with the extension of perifoveal retinal thickening seen in Stratus OCT and not with the clinical appearance. In contrast, partial–thickness holes never show an absolute central scotoma in functional mapping. Typically, a relative scotoma is found in this subgroup which is substantially smaller in comparison to the relative defect seen in full–thickness holes. Conclusions: Functional macular mapping using Nidek MP1 provides additional information regarding functional loss in full thickness macular holes and is able to differentiate full–thickness from partial–thickness macular holes.
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