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Y. Noda, M. Miyazaki, S. Shiose, T. Kita, K. Hirayama, Y. Hata, K. Fujisawa, T. Ishibashi; Sort–Term Visual Outcome of PDT for Japanese AMD Patients . Invest. Ophthalmol. Vis. Sci. 2005;46(13):302.
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© ARVO (1962-2015); The Authors (2016-present)
Purpose: To investigate the short–term effect of photodynamic therapy (PDT) on the visual outcome of Japanese patients with age–related macular degeneration (AMD). Methods: Thirty one Japanese patients underwent PDT at Kyushu University for the treatment of AMD was enrolled. The patients’ height, body weight, blood count, serum biochemistry, greatest linear dimension (GLD) and lesion composition were examined, respectively. Smoking history, medical problem, and daily use medicines were also inquired. The effects of PDT were assessed by best corrected visual acuity (BCVA), foveal thickness and GLD. Results: Average of BCVA, GLD and foveal thickness were improved 3/20 to 6/20, 3192µm to 2163µm, and 357µm to 292µm (p<0.05, respectively), at the time point of 3 months after PDT. Body mass index negatively correlated with the improvement level of BCVA (p<0.05). Conclusions: PDT seems to be beneficial for Japanese AMD patients at least in short–term. Long time observation is necessary to clarify whether systemic condition of respective patients might affect the therapeutic effect of PDT.
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