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S. Ishiko, H. Kagokawa, A. Takamiya, J. Takahashi, Y. Kato, T. Nagaoka, S. Igarashi, R. Kinouchi, K. Fukui, A. Yoshida; Early Visual Acuity After Photodynamic Therapy and SLO Microperimetry . Invest. Ophthalmol. Vis. Sci. 2005;46(13):306.
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© ARVO (1962-2015); The Authors (2016-present)
Purpose:To investigate the relation between the early visual acuity (VA) results after photo dynamic therapy (PDT) and scanning laser ophthalmoscopy (SLO) microperimetric findings before PDT. Methods: Nine patients (9 eyes; 6 men, 3 women; 63–84 years old) who underwent PDT were included. We evaluated the preferred retinal locus (PRL) and scotoma using SLO microperimetry before PDT. Results: The mean VA levels before and 10 days after PDT were 0.2–1.1 and 0.15–1.05 (log MAR), respectively. A significant VA improvement occurred in three eyes with the PRL at the fovea and no scotoma near the PRL. Two eyes with an eccentric PRL outside the central scotoma and four eyes with a scotoma close to or at the fovea and no established new PRL did not have a significant VA change. Conclusions: Eyes with good foveal function before PDT might have early VA improvement after PDT. Evaluation of the PRL and the scotoma around the fovea using SLO microperimetry should be performed before PDT.
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