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H.J. Koh, S.H. Byeon, S.C. Lee, O.W. Kwon; ICG Angiographic Features of Myopic Subfoveal Choroidal Neovascularization as a Prognostic Factor Influencing Visual Outcome After Photodynamic Therapy . Invest. Ophthalmol. Vis. Sci. 2005;46(13):327.
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© ARVO (1962-2015); The Authors (2016-present)
Purpose: To determine the influence of ICG angiographic features and age on the visual outcome of patients with myopic subfoveal choroidal neovascularization(CNV) who received photodynamic therapy (PDT). Methods: Thirty consecutive eyes (28 patients) with myopic CNV after PDT more than 1 year follow up were enrolled in this study. General Linear Model Analysis was performed to assess the association of visual acuity outcome with prognostic factors of age and ICG angiographic features. ICG features included the dark rim surrounding the CNV, choroidal vascular abnormalities, lacquer cracks, peripapillary atrophy and hemorrhage. Results: Older Age (p = 0.010) and choroidal vascular abnormalities ( p = 0.043 ) significantly correlated with poor visual outcome, while dark rim ( p = 0.001) correlated with good visual outcome. Conclusions: ICG angiographic features of myopic CNV such as dark rim and choroidal vascular abnormalities were significant prognostic factors of visual outcome after PDT. These ICG angiographic features may be more predictable than age which is known to be a prognostic factor.
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