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S. Nunes, J.P. Figueira, R.C. Bernardes, J.G. Cunha–Vaz; Mild CSME Measured by RTA I and OCT II. Correlation With Fundusphotography . Invest. Ophthalmol. Vis. Sci. 2005;46(13):348.
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© ARVO (1962-2015); The Authors (2016-present)
Purpose: To assess the classification of mild CSME based on the RTA I (Talia Technology, Ltd, Lod Indst. Area, Israel) and OCT II (Humphrey Instruments, Calif. USA) versus fundus photography. Methods: Fourteen–eyes from 14 patients, aged from 29 to 68 years–old (mean ± SD: 56 ± 11), 10 males and 4 females, were selected as having CSME based on color fundus photography classifiyed by independent graders. These eyes were also submitted within a 4 weeks time period to RTA I and OCT II analysis. From the OCT, 9 areas were considered and compared to a reference map. For the RTA, two maps were created, one that mimics the OCT map and one that provides more detailed information on a total of 54 areas in a total of three concentric donut–like shape, plus 4 central values. Results: On the OCT map, it was possible to find increased retinal thickness in only 6 out of the 14 CSME–eyes (5 in <font face="symbol">Æ</font>< 1000 µm and 4 in 1000 µm< <font face="symbol">Æ</font>< 3000 µm). On the RTA maps similar to the OCT ones, it was possible to find increased thickness in only 8 out of the 14 CSME–eyes (6 in <font face="symbol">Æ</font>< 1000 µm; 8 in 1000 µm < <font face="symbol">Æ</font> < 3000 µm). Using the newly developed RTA maps, it was possible to find increased retinal thickness in 11 out of 14 eyes (3 in the central 500 µm, 11 in 500 µm < <font face="symbol">Æ</font><1500 µm, 7 in 1500 µm < <font face="symbol">Æ</font> < 2500 µm). Two of the tree eyes that were considered edema–free by the RTA (retinal thickness within normal range) had hard exudates on fundus photography. Conclusions: The RTA, by providing a more detailed mapping using a proprietary software, found increased retinal thickness in 11 out of 14 CSME–eyes. Eyes may be diagnosed as CSME by fundus photography due to the presence of hard exudates even having retinal thickness measurements within normal range.
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