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S. Cavarretta, C. Teodori, S. Lupo, D. Domanico, E.M. Vingolo; Optical Coherence Tomography: Hight Sensitive Diagnostic Test for Retinal Changes in Retinitis Pigmentosa . Invest. Ophthalmol. Vis. Sci. 2005;46(13):526.
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© ARVO (1962-2015); The Authors (2016-present)
Objective: To evaluate retinal thickness, cystoid macular oedema, cellophane, optic nerve head drusen in patients with retinitis pigmentosa by optical coherence tomography . Methods: 25 patients ( 50 eyes) with RP followed in our department of Ophthalmology " La Sapienza" University of Rome, underwent to best corrected visual acuity, applanation Goldmann tonometry, slit–lamp biomicroscopy and indirect opthalmoscopic examination (Schepen’s), manual perimetry, electroretinogramm , fluorangiography and OCT stratus III (retinal map analysis, retinal thickness, optic nerve head analyzer, RNFL thickness average). Results: OCT showed common future of the retinitis pigmentosa in all patients: a reduced retinal thickness with an atrophy of the photoreceptors layer (32 eyes), alteration of the retinal reflectivity (15 eyes cellophane, 4 eyes pucker, 7 eyes macular hole), cystoid macular oedema (18 eyes) and optic nerve head drusen (2 eyes). Conclusions: OCT appears useful for objectively monitoring the natural history or under treatment in patients with retinal thickness, alteration of the retinal reflectivity, CME and OPHD. It had demonstrated to be an hight sensitive diagnostic test for study the typical retinal aspects in retinitis pigmentosa: diagnosis, therapy and macular's diseases follow up.
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