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R.D. Ferguson, D.X. Hammer, N.V. Iftimia, G. Wollstein, H. Ishikawa, M.L. Gabriele, W. Dilworth, A.A. Bonfioli, J.S. Schuman; Enhanced Retinal Imaging With Tracking Optical Coherence Tomography (TOCT) . Invest. Ophthalmol. Vis. Sci. 2005;46(13):1118.
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© ARVO (1962-2015); The Authors (2016-present)
Purpose: To enable new and improved retinal OCT imaging and image analysis with a high speed closed–loop eye tracking system integrated into a new clinical OCT instrument. Methods: A high speed retinal tracker system was integrated into a clinical optical coherence tomography system (StratusOCT, Carl Zeiss Meditec Inc, Dublin, Ca). The hybrid instrument, called tracking optical coherence tomography (TOCT), uses a secondary sensing beam in a confocal reflectometer and steering mirrors to compensate eye motion with a closed loop bandwidth of 1 kHz and a lateral rms accuracy ∼15 µm. Imaging and tracking control systems have been integrated into a single platform and user interface in order to admit new imaging capabilities and considerable simplification in acquisition of clinical data. The system was configured to acquire high–resolution retinal maps through all subject eye movements and blinks, without disruption of complex scan sequences or loss of data. Results: Five normal subjects were scanned with a non–standard TOCT scan protocol that included up to 24 repeated high resolution peripapillary and radial disc scans, and high density raster scans of both the optic nerve head and the macula. The new TOCT system achieves highly accurate OCT scan registration yielding averaged (co–added) images with significantly improved appearance and signal–to–noise ratio while maintaining well–defined boundaries and sharp fine structure. Precise re–registration of multiple scans over separate imaging sessions demonstrates TOCT utility for longitudinal studies. Long duration raster scans enable detailed mapping of large tissue volumes despite eye motion. Conclusions: The capability to reproducibly map structures in the living eye at high resolution will lead to improved understanding of disease processes and improved sensitivity and specificity of diagnostic procedures. Tracking systems are expected to augment the capabilities of future high–speed SDOCT systems.
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