May 2005
Volume 46, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2005
Opacification of Hydroview Hydrogel Intraocular Lens: Analysis of 3 Explanted Lenses
Author Affiliations & Notes
  • S. Nakanome
    1st Dept Ophthalmology, Toho University Sch Med, Tokyo, Japan
  • Footnotes
    Commercial Relationships  S. Nakanome, Koichiro Tanaka F; Hiroshi Watanabe F; Shinichiro Kobayakawa F; Tetsuo Tochikubo F.
  • Footnotes
    Support  None.
Investigative Ophthalmology & Visual Science May 2005, Vol.46, 707. doi:
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      S. Nakanome; Opacification of Hydroview Hydrogel Intraocular Lens: Analysis of 3 Explanted Lenses . Invest. Ophthalmol. Vis. Sci. 2005;46(13):707.

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Abstract

Abstract: : Purpose: To report on the clinical, electron microscopic, and x–ray spectroscopic analyses of opacificated Hydroview intraocular lenses (IOLs) involving 3 explanted cases. Methods: 3 Hydroview IOLs were explanted from 2 patients in an average of 20 months after IOL implantation due to decreased visual acuity. The 3 IOLs were examined by light, scanning electron microscopy, and energy dispersion x–ray spectroscopy (EDS). Results: Using a scanning electron microscope, we observed that the front and backs of all 3 IOL optics were uniformly opacificated with spherical deposits of approximately 1–10 µm in diameter. However, there were areas of particularly dense and hard opacification in the form of 2 straight lines (rectilinear opacification) on the fronts of each examined IOL optic. EDS showed that all opacification consisted mainly of calcium and phosphate. However, no silicon was detected.We believe that the rectilinear opacification were marks caused by the forceps used during IOL implantation since the marks were observed on the front surface and in 2 places in each examined case. Conclusions: We believe that the rectilinear opacification was caused by the mechanical compression of the forceps, which changed the configuration of the IOLs.

Keywords: cataract • calcium • microscopy: electron microscopy 
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