May 2005
Volume 46, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2005
Measurement of the Lens Capsule Contraction Force in the Radial Direction
Author Affiliations & Notes
  • J. Shen
    Vanderbilt Eye Institute, Vanderbilt University, Nashville, TN
  • D.M. O'Day
    Vanderbilt Eye Institute, Vanderbilt University, Nashville, TN
  • Footnotes
    Commercial Relationships  J. Shen, Vanderbilt University P; D.M. O'Day, None.
  • Footnotes
    Support  The Whitaker Foundation Biomedical Engineering Grant.
Investigative Ophthalmology & Visual Science May 2005, Vol.46, 728. doi:
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      J. Shen, D.M. O'Day; Measurement of the Lens Capsule Contraction Force in the Radial Direction . Invest. Ophthalmol. Vis. Sci. 2005;46(13):728.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Abstract: : Purpose:We have designed an accommodative IOL, which uses the contraction force of the lens capsule to change the diameter of the IOL, and thus induce the diopter change. The purpose of this study is to measure the contraction force of the lens capsule in the radial direction. Methods:Eight mini stress sensor were fabricated, with each consisting of a mini probe head. These sensors were mounted onto an adjustable diameter device, so that the probe head of the sensors were symmetrically arranged into a circle. Fresh animal cadaver eyes were dissected, so that the lenses with iris and ciliary muscle together were obtained. Capsulorrhexis was performed on the anterior surface of the lens. Lens contents were removed. The probe heads of the mini sensor were inserted into the opening of the lens capsule. When the diameter of the sensor structure changed, the contraction force of the lens capsule in the radial direction could be measured. Results:When the outer diameter of the lens capsule changes 0.5 mm, the contraction force of each sensor changed 1.8±1 g. Conclusions:The measurement of the contraction force of the lens capsule will help the determination of the accommodative IOL parameters.

Keywords: cataract • ciliary muscle • crystallins 
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