May 2005
Volume 46, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2005
Antibody Profile Studies of Human Pterygium
V.K. Sharma; S. Kashani; D. Hopster; R. Sandhu; P.A. Hunter
Author Affiliations & Notes
  • V.K. Sharma
    Ophthalmology, kings college london, London, United Kingdom
  • S. Kashani
    Ophthalmology, Kings College London, London, United Kingdom
  • D. Hopster
    Ophthalmology, Kings College London, London, United Kingdom
  • R. Sandhu
    Ophthalmology, Kings College London, London, United Kingdom
  • P.A. Hunter
    Ophthalmology, Kings College London, London, United Kingdom
  • Footnotes
    Commercial Relationships  V.K. Sharma, None; S. Kashani, None; D. Hopster, None; R. Sandhu, None; P.A. Hunter, None.
  • Footnotes
    Support  None.
Investigative Ophthalmology & Visual Science May 2005, Vol.46, 965. doi:
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      V.K. Sharma, S. Kashani, D. Hopster, R. Sandhu, P.A. Hunter; Antibody Profile Studies of Human Pterygium . Invest. Ophthalmol. Vis. Sci. 2005;46(13):965.

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Abstract

Abstract: : Purpose: To evaluate the antibody profile of pterygium tissue. Methods: 21 human pterygium tissue and 6 conjunctival controls were stained using direct immunofluorescence for the different types of antibodies present Results: An increased amount of IgE and IgA ( in both plasma cells and perivascular ) was found in pterygium tissue than in the controls. IgG was present in all specimens but very little IgM was found in the pterygium tissue. Conclusions: An immunological mechanism, possibly a type 1 hypersensitivity reaction, may be involved in the pathogenesis of pterygium

Keywords: Pterygium • immunohistochemistry • microscopy: light/fluorescence/immunohistochemistry 
© 2005, The Association for Research in Vision and Ophthalmology, Inc., all rights reserved. Permission to republish any abstract or part of an abstract in any form must be obtained in writing from the ARVO Office prior to publication.
Copyright © 2024 Association for Research in Vision and Ophthalmology.
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