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V.K. Sharma, S. Kashani, D. Hopster, R. Sandhu, P.A. Hunter; Antibody Profile Studies of Human Pterygium . Invest. Ophthalmol. Vis. Sci. 2005;46(13):965.
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Purpose: To evaluate the antibody profile of pterygium tissue. Methods: 21 human pterygium tissue and 6 conjunctival controls were stained using direct immunofluorescence for the different types of antibodies present Results: An increased amount of IgE and IgA ( in both plasma cells and perivascular ) was found in pterygium tissue than in the controls. IgG was present in all specimens but very little IgM was found in the pterygium tissue. Conclusions: An immunological mechanism, possibly a type 1 hypersensitivity reaction, may be involved in the pathogenesis of pterygium
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