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A. Hagiwara, K. Okada, S. Mizunoya, S. Yamamoto; Correlation of Retinal Sensitivity Measured by Fundus–related Microperimetry to Visual Acuity and Retinal Thickness in Eyes With Macular Edema . Invest. Ophthalmol. Vis. Sci. 2005;46(13):1560.
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© ARVO (1962-2015); The Authors (2016-present)
Purpose: To study the correlation of retinal sensitivity measured by fundus–related microperimetry to the visual acuity and the OCT–determined foveal thickness in eyes with macular edema (ME). Methods: A retrospective chart review was made of eyes with ME that had had fundus–related microperimetry and OCT performed. Thirty–four eyes with macular edema due to branch retinal vein occlusion or diabetic retinopathy, and 17 normal healthy eyes were studied. The macular sensitivity (decibels) was measured using the fundus–related microperimeter. The correlations between the mean retinal sensitivities at the central 2 degrees and 10 degrees to the best–corrected visual acuity and to the OCT–determined foveal thickness were calculated. Results: The mean sensitivities at central 2 degrees and 10 degrees for eyes with ME were significantly lower than those for normal subjects (P <0.0001). The mean retinal sensitivities at the central 2 degrees and 10 degrees were inversely correlated with the visual acuity (r2=0.715, P<0.0001; r2=0.648, P<0.0001), and foveal thickness (r2=0.482, P<0.0001; r2=0.497, P<0.0001). Conclusions: The mean retinal sensitivity measured by fundus–related microperimetry was significantly lower in eyes with macular edema than in normal eyes. Because of the significant linear correlation of the microperimeter–determined retinal sensitivity to visual acuity and foveal thickness, fundus–related microperimetry may be another objective method to assess the effect of macular edema on retinal function.
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