Abstract
Abstract: :
Purpose: The OCT Opthalmoscope is a new device which provides high resolution cross sectional (longitudinal, B–scan) and coronal (transversal, C–scan) images of the posterior fundus. To correlate OCT Ophthalmoscopy with angiographic signs of polypoidal choroidal neovascularization (CNV) in eyes with polypoidal choroidal vasculopathy (PCV), we examined patients with OCT Opthalmoscope. Methods: We prospectively examined 50 consecutive eyes (48 patients; 36 men, 12 women) with PCV using OCT Opthalmoscope, fluorescein and indocyanine green (ICG) angiography. Patients ranged in age from 50 to 90 years, average 72 years. Twenty–one of the 50 eyes had a serous retinal pigment epithelial detachment (PED). Results: ICG angiography showed polypoidal CNV in all eyes. B–scan images of OCT Ophthalmoscope clearly demonstrated anterior protrusions of highly reflective layer corresponding to polypoidal CNV. C–scan images of eyes without PED revealed distinctive bright rings similar to the PED corresponding to the polypoidal CNV in 27 of 29 eyes. C–scan images of eyes with PED showed irregularity or protrusion in PED at the area of polypoidal CNV in 21 of 21 eyes. Conclusions: Our current OCT Ophthalmoscopic and angiographic study revealed that irregularity or protrusion in the PED and angiographic polypoidal CNV had close correspondence. Eyes without PED had distinctive bright rings corresponding to the polypoidal CNV. These OCT Ophthalmoscopic findings may be diagnostically important as an indication of polypoidal CNV in eyes with PCV.
Keywords: age-related macular degeneration • imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) • retinal neovascularization