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R.F. Lam, S.K. Rao, D.S. P. Fan, D.S. C. Lam; Macular Pigment Optical Density in a Chinese Sample . Invest. Ophthalmol. Vis. Sci. 2005;46(13):1761.
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© ARVO (1962-2015); The Authors (2016-present)
Extensive efforts have been devoted to determining the MacularPigment Optical Density (MPOD) in Caucasian subjects. Unfortunatelyno such data in ethnic groups with naturally dark irides, suchas the Chinese, are currently available. In this study, we reportthe values in a sample of Chinese subjects.
The MPOD was measured psychophysically using a Densitometerat 0.25°, 0.50°, 1.00° and 2.00° eccentricityfrom the foveal center. Ninety–two ethnic Chinese subjectsranging in age from 16 to 85 (mean 39.1) years were studied.
The spatial profile for the averaged MPOD was approximatelyexponential in form (Figure 1) and showed a decline with age(r = –0.23, Figure 2). The averaged MPOD in log unitsat 1.00° eccentricity for subjects aged <20, ≥20 &<40, ≥40 & <60, ≥60 years were 0.37, 0.33, 0.32 and0.20 respectively. Subjects aged below 60 years had a significantlyhigher averaged MPOD than those aged 60 years or above. Significantgender differences, in favor of males, were also found in themiddle age–groups. There were no significant interoculardifferences.
Our study reports for the first time, the MPOD in a Chinesepopulation. The observed age and gender distribution in Chinesesubjects concur with the recently published Western data. Baselineinformation on MPOD would aid future research in preventivemeasures against age–related macular degeneration.
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