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L.M. Renzi, B.R. Hammond, Jr; The Relation Between Macular Pigment and Serum Triglyceride Levels . Invest. Ophthalmol. Vis. Sci. 2005;46(13):1775.
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Purpose: A number of studies have shown a strong inverse relation between macular pigment optical density (MPOD) and obesity. Of the many lipid fractions, triglycerides may be the most strongly influenced by dietary fat intake and adiposity. For example, most body fat is in the form of triglycerides stored in adipose tissue. Thus, MP may also be related to triglyceride levels. In the present study, we assessed this hypothesis. Methods: Serum triglycerides were assessed via the Cholestech LDX portable lipid analyzer in 36 participants (M = 58 yrs, range = 31–75 yrs). MPOD was assessed using HFP in Newtonian view according to the CAREDS protocol. Results: A significant, inverse relation was found between serum triglycerides and MPOD (r = –0.38, p<0.01). This relation was not influenced by age. Conclusions: High triglyceride levels and low MP density have been identified as possible risk factors for age–related macular degeneration (AMD). Our preliminary results suggest that these two factors may covary. Results regarding the relation between MP and the full lipid profile will be presented and discussed.
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