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R.M. Vessani, A.P. Raiza, M. Hatanaka, R. Susanna; Comparison of Different Stratus OCT Protocols for Glaucoma Detection . Invest. Ophthalmol. Vis. Sci. 2005;46(13):2516.
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© ARVO (1962-2015); The Authors (2016-present)
Purpose: To evaluate and compare the ability of peripapillary RNFL measurements, macular thickness measurements and optic disc measurements by optical coherence tomography (Stratus OCT) to discriminate between healthy eyes and eyes with glaucoma. Methods: Twenty–seven patients with glaucomatous visual field loss and 35 healthy subjects with similar age underwent imaging in one eye with "Fast RNFL thickness(3.4)", "Fast Macular Thickness Map" and "Fast Optical Disc" scan protocols of the StratusOCT. Visual field testing was perfomed in all subjects within a 6–month period. Average MD (± SD) of the visual field tests of glaucomatous patients was –6.60 ± 5.68 dB. ROC curves and sensitivities at fixed specificities were calculated for parameters reported as continuous variables on the clinical printout of each scan protocol of the instrument. Results: Area under the ROC curve (AUC) was higher for mean RNFL thickness (0.93), RNFL thickness measured at 6 o’clock (0.92), vertical integrated rim area (0.92) and horizontal integrated rim width (0.92). The best Macular Thickness Map parameter, superior outer macula, showed significantly lower AUC (0.79) compared to previous parameters. Conclusions:Peripapillary RNFL and optic disc parameters provided better performance than macula thickness parameters to differentiate glaucomatous from normal eyes.
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