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N. Sekhon, A. Venkataraman, D.L. Budenz; Relationship Between Optical Coherence Tomography Retinal Nerve Fiber Thickness Measurements and Visual Field Abnormalities Measured by Standard Automated Perimetry in Glaucomatous Eyes . Invest. Ophthalmol. Vis. Sci. 2005;46(13):2538.
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© ARVO (1962-2015); The Authors (2016-present)
To establish topographical correlation between the peripapillary Optical Coherence Tomography’s (STRATUS OCT) measurements of RNFL with visual field defects in glaucomatous eyes.
78 eyes of 78 glaucoma patients were enrolled in the study. Each patient had undergone OCT testing using 3.4mm fast scans around the ONH and standard white–on–white Humphrey automated perimetry within 6 months of each other. The four quadrants were labeled temporal, superior, nasal, and inferior about the ONH based on Garway–Heath’s optic nerve head mapping scheme. The visual field test points were grouped into the corresponding four sectors. The test points in each of the visual field sector were summed and the sum of each visual field sector was then compared to the data obtained from the corresponding quadrant of the OCT scans. The data was analyzed using Pearson’s correlation coefficient in order to establish the relationship between the structural damage seen on the OCT and functional deficit
The 78 patients (71.2 yrs ± 11.8 yrs) included 49(63%) females and 29(37%) males with glaucoma severity evenly distributed across the spectrum.
RNFL thickness average as measured by STRATUS OCT correlates well with MD and PSD on standard automated perimetry, suggesting a compelling relationship between RNFL thinning and visual field loss. The visual field sectors correlated well with corresponding quadrants of the OCT.
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