May 2005
Volume 46, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2005
Discomfort With Dilating Eye Drops: a Comparison With and Without Prior Anesthetic Drops
Author Affiliations & Notes
  • K. Wals
    Ophthalmology, Montefiore Medical Center, Bronx, NY
  • J. Levine
    Ophthalmology, Montefiore Medical Center, Bronx, NY
  • Footnotes
    Commercial Relationships  K. Wals, None; J. Levine, None.
  • Footnotes
    Support  None.
Investigative Ophthalmology & Visual Science May 2005, Vol.46, 2653. doi:
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      K. Wals, J. Levine; Discomfort With Dilating Eye Drops: a Comparison With and Without Prior Anesthetic Drops . Invest. Ophthalmol. Vis. Sci. 2005;46(13):2653.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Abstract: : Purpose: To determine if prior administration of an anesthetic drop alters the amount of discomfort experienced with the administration of dilating drops. Methods: Subjects were screened for any external ocular disease precluding normal corneal sensation. 20 subjects then, with randomization, received topical tetracaine 0.5% followed by tropicamide 1% and phenylephrine 2.5% in one eye, and tropicamide and phenylephrine without tetracaine in the other eye. On a scale of 1 to 10 (10 being the greatest), subjects then stated the amount of discomfort experienced with the application of each set of drops. Results: The mean discomfort with the use of tetracaine was 3.04, versus 3.38 without tetracaine. The mean difference in discomfort was greater without prior anesthetic drops by only 0.34 (+/–1.97). Conclusions: Prior administration of topical anesthetic eye drops does not significantly alter the discomfort experienced with the application of dilating drops.

Keywords: cornea: epithelium • drug toxicity/drug effects • cornea: clinical science 
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