May 2005
Volume 46, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2005
Corneal Reinnervation After Penetrating Keratoplasty
Author Affiliations & Notes
  • M.A. Wassfi
    Ophthalmology, Hospital Clinico San Carlos, Madrid, Spain
  • J.M. Benitez–del–Castillo
    Ophthalmology, Hospital Clinico San Carlos, Madrid, Spain
  • D. Diaz–Valle
    Ophthalmology, Hospital Clinico San Carlos, Madrid, Spain
  • J. Garcia–Feijoo
    Ophthalmology, Hospital Clinico San Carlos, Madrid, Spain
  • J. Garcia–Sanchez
    Ophthalmology, Hospital Clinico San Carlos, Madrid, Spain
  • Footnotes
    Commercial Relationships  M.A. Wassfi, None; J.M. Benitez–del–Castillo, None; D. Diaz–Valle, None; J. Garcia–Feijoo, None; J. Garcia–Sanchez, None.
  • Footnotes
    Support  None.
Investigative Ophthalmology & Visual Science May 2005, Vol.46, 2701. doi:
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    • Get Citation

      M.A. Wassfi, J.M. Benitez–del–Castillo, D. Diaz–Valle, J. Garcia–Feijoo, J. Garcia–Sanchez; Corneal Reinnervation After Penetrating Keratoplasty . Invest. Ophthalmol. Vis. Sci. 2005;46(13):2701.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Abstract: : Purpose: The aim of the study was to assess corneal reinnervation and the density of superficial epithelial corneal cells (SECC) following penetrating keratoplasty (PK). Methods: A Tomey Confoscan slit–scanning confocal microscope was used to examine corneal grafts in vivo. A total of 20 eyes were examined 1, 3, 6 and 12 months after PK. Results: The first stromal nerves were detected one month after PK in 18/20 eyes while the subbasal nerves were first observed one year following the operation. The density of SECC was constant and similar to that of healthy corneas. Conclusions: Corneal reinnervation following PK is mainly influenced by the amount of time elapsing after surgery and it is not affected neither by age nor by preoperative diagnosis.

Keywords: cornea: epithelium • transplantation • cornea: clinical science 
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