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M.A. Wassfi, J.M. Benitez–del–Castillo, D. Diaz–Valle, J. Garcia–Feijoo, J. Garcia–Sanchez; Corneal Reinnervation After Penetrating Keratoplasty . Invest. Ophthalmol. Vis. Sci. 2005;46(13):2701.
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Purpose: The aim of the study was to assess corneal reinnervation and the density of superficial epithelial corneal cells (SECC) following penetrating keratoplasty (PK). Methods: A Tomey Confoscan slit–scanning confocal microscope was used to examine corneal grafts in vivo. A total of 20 eyes were examined 1, 3, 6 and 12 months after PK. Results: The first stromal nerves were detected one month after PK in 18/20 eyes while the subbasal nerves were first observed one year following the operation. The density of SECC was constant and similar to that of healthy corneas. Conclusions: Corneal reinnervation following PK is mainly influenced by the amount of time elapsing after surgery and it is not affected neither by age nor by preoperative diagnosis.
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