May 2005
Volume 46, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2005
Corneal Reinnervation After Penetrating Keratoplasty
M.A. Wassfi; J.M. Benitez–del–Castillo; D. Diaz–Valle; J. Garcia–Feijoo; J. Garcia–Sanchez
Author Affiliations & Notes
  • M.A. Wassfi
    Ophthalmology, Hospital Clinico San Carlos, Madrid, Spain
  • J.M. Benitez–del–Castillo
    Ophthalmology, Hospital Clinico San Carlos, Madrid, Spain
  • D. Diaz–Valle
    Ophthalmology, Hospital Clinico San Carlos, Madrid, Spain
  • J. Garcia–Feijoo
    Ophthalmology, Hospital Clinico San Carlos, Madrid, Spain
  • J. Garcia–Sanchez
    Ophthalmology, Hospital Clinico San Carlos, Madrid, Spain
  • Footnotes
    Commercial Relationships  M.A. Wassfi, None; J.M. Benitez–del–Castillo, None; D. Diaz–Valle, None; J. Garcia–Feijoo, None; J. Garcia–Sanchez, None.
  • Footnotes
    Support  None.
Investigative Ophthalmology & Visual Science May 2005, Vol.46, 2701. doi:
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      M.A. Wassfi, J.M. Benitez–del–Castillo, D. Diaz–Valle, J. Garcia–Feijoo, J. Garcia–Sanchez; Corneal Reinnervation After Penetrating Keratoplasty . Invest. Ophthalmol. Vis. Sci. 2005;46(13):2701.

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Abstract

Abstract: : Purpose: The aim of the study was to assess corneal reinnervation and the density of superficial epithelial corneal cells (SECC) following penetrating keratoplasty (PK). Methods: A Tomey Confoscan slit–scanning confocal microscope was used to examine corneal grafts in vivo. A total of 20 eyes were examined 1, 3, 6 and 12 months after PK. Results: The first stromal nerves were detected one month after PK in 18/20 eyes while the subbasal nerves were first observed one year following the operation. The density of SECC was constant and similar to that of healthy corneas. Conclusions: Corneal reinnervation following PK is mainly influenced by the amount of time elapsing after surgery and it is not affected neither by age nor by preoperative diagnosis.

Keywords: cornea: epithelium • transplantation • cornea: clinical science 
© 2005, The Association for Research in Vision and Ophthalmology, Inc., all rights reserved. Permission to republish any abstract or part of an abstract in any form must be obtained in writing from the ARVO Office prior to publication.
Copyright © 2015 Association for Research in Vision and Ophthalmology.
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