May 2005
Volume 46, Issue 13
ARVO Annual Meeting Abstract  |   May 2005
Microkeratome–Assisted Endothelial Lamellar Keratoplasty
Author Affiliations & Notes
  • M. Omoto
    Ophthalmology, Tokyo Dental College, Ichikawa, Japan
  • S. Shimmura
    Ophthalmology, Tokyo Dental College, Ichikawa, Japan
  • K. Tsubota
    Ophthalmology, Keio University School of Medicine, Tokyo, Japan
  • J. Shimazaki
    Ophthalmology, Tokyo Dental College, Ichikawa, Japan
  • Footnotes
    Commercial Relationships  M. Omoto, None; S. Shimmura, None; K. Tsubota, None; J. Shimazaki, None.
  • Footnotes
    Support  None.
Investigative Ophthalmology & Visual Science May 2005, Vol.46, 2702. doi:
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    • Get Citation

      M. Omoto, S. Shimmura, K. Tsubota, J. Shimazaki; Microkeratome–Assisted Endothelial Lamellar Keratoplasty . Invest. Ophthalmol. Vis. Sci. 2005;46(13):2702.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract: : Purpose: To report the result of case series of 9 patients who underwent endothelial keratoplasty (microkeratome–assisted posterior keratoplasty). Methods: A retrospective case series was performed on 9 eyes of 9patients with bullous keratopathy. A microkeratome was used to create a hinged anterior corneal flap in the host cornea, and donor tissue was prepared using an artificial anterior chamber. The hinged anterior flap was replaced over the donor button and only the flap was sutured with 10–0 nylon. Two patients underwent concurrent extracapsular cataract extraction or phacoemulsification with posterior chamber lens implantation. Results: At six months after surgery all grafts were clear and well positioned, but two flaps were hazy. At six months follow–up the best–corrected visual acuity ranged 20/30 to 20/200, and the average astigmatism was 3.8±3.6 diopters. Mean endothelial cell count was 1212±513.1 cell/mm². Complications included two episodes of diffuse lamellar keratitis responsive to steroids, and two episodes of the donor button detachment from the flap treated by air injection to the anterior chamber. One patient required resuturing of the flap one week post–operatively. Conclusions: These results indicate that endothelial lamellar keratoplasty is effective to treat bullous keratopathy. Our initial results must be confirmed in lager population followed over several years.

Keywords: cornea: epithelium • clinical (human) or epidemiologic studies: outcomes/complications 

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