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N. Tou, A. Tawara; Species of Bacteria and Their Sensitivity to Antibiotics in Eye Discharge in Japanese Hospitalized Patients . Invest. Ophthalmol. Vis. Sci. 2005;46(13):2776.
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Purpose: To investigate both species of bacteria and their sensitivity to antibiotics in eye discharge. Methods: We cultivated eye discharges from 423 Japanese patients admitted in a general hospital during 6 years through 1998, and detected their resistant rate to antibiotics. Results: By culture, 678 strains of bacteria were detected. Corynebacterium sp. was the most common (156 strains, 23.0%). Following Methicillin–resistant Staphylococcus aureus (MRSA) and Coagulase negative staphylococcus (CNS) were 145 strains (21.4%) and 136 strains (20.1%) respectively. There were 561 strains of gram–positive bacteria as a whole. Their resistant rates were 37.6% for cefmenoxime, 18.2% for chloramphenicol, 60.3% for ofloxacin. The rate of resistant of Corynebacterium sp. was 1.0% for cefmenoxime, 25.0% for chloramphenicol, 59.6% for ofloxacin. That of MRSA was 100% for cefmenoxime, 9.0% for chloramphenicol, 95.9% for ofloxacin, 20.0% for oxytetoracyclin, nil for vancomicin. That of CNS was 40.4% for cefmenoxime, 33.8% for chloramphenicol, 61.0% for ofloxacin. Conclusions:Following Corynebacterium sp. and MRSA, the common bacteria that isolated from eye discharge was CNS. The findings show that Cefmenoxime and Chloramphenicol are more effective than Ofloxacin for gram–psitive bacteria that are common in the conjunctigal sac.
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