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R.N. G. Vianna, P.Ç. Ozdal, J.P. Souza Filho, V.S. Saraiva, M.P. Ventura, J. Deschenes, M.N. Burnier, Jr; Long–term Follow–up of Patients With Multifocal Choroiditis and Panuveitis . Invest. Ophthalmol. Vis. Sci. 2005;46(13):2827.
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Purpose: To report the visual prognosis and long–term complications in patients with multifocal choroiditis and panuveitis (MCP). Methods: A retrospective study was performed with patients who met inclusion criteria for MCP at the Uveitis Clinic, Royal Victoria Hospital, McGill University, Montreal, Canada. Information collected included duration of follow–up, visual acuity (VA) measured at each clinical visit, ocular and systemic treatment and ocular complications observed during the follow–up. Results: Nineteen patients (37 eyes) with MCP with a mean follow–up of 76.9 months were studied. Kaplan–Meier survival analysis showed a decrease in the proportion of patients with a final VA of 20/40 or better over time. Cystoid macular edema was seen in 29.7% of the eyes and was the most frequent macular abnormality observed in our group. On the other hand, choroidal neovascularization was detected in only 6 (16.2%) of the eyes, but was related to a visual acuity of less than 20/200 in four of these eyes. Glaucoma was detected in 10.8% of the eyes. Cataract (posterior subcapsular and/or nuclear) was the most common long–term complication, occurring in 40% of the affected eyes. Cataract surgery improved the visual acuity in 83.3% of these eyes. Conclusions: The visual acuity of patients with MCP decreases with time. Visual loss can occur from complications following the inflammation itself and/or iatrogenic induced by the chronic use of corticosteroids.
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