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H. Matsushima, H. Iwamoto, K. Mukai, Y. Obara; Novel Active Oxygen Processing for Acrylic Intra Ocular Lens to Prevent Secondary Posterior Capsular Opacification . Invest. Ophthalmol. Vis. Sci. 2005;46(13):2854. doi: https://doi.org/.
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© ARVO (1962-2015); The Authors (2016-present)
Evaluation of active oxygen processing on surface of acrylic intraocular lens to prevent secondary posterior capsular opacification (PCO).
Acrylic IOLs were prepared and ultra violet rays were irradiated to active oxygen processing the surface of IOLs. The treated IOLs and control IOLs were prepared for experiments. Eight–week old albino rabbits were anesthetized and phacoemulcification were performed. The treated IOLs were implanted into right eye and the control IOLs were implanted into left eye. After 2 weeks, the rabbits were euthnized and their eye balls were dissected and fixed using 10% formaldehyde. The developed PCOs were observed using light microscopy (DX51, ORIMPUS) after hematoxylin and eosin staining.
The thickness of PCO in center was 55 µm using control IOLs; however, it was 15 µm using treated IOLs. Development of PCO was prevented using treated acrylic IOLs by increasing adhesion with posterior capsule.
An active oxygen processing on surface of IOLs is novel effective method to prevent secondary PCO after cataract surgery.
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