May 2005
Volume 46, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2005
Novel Active Oxygen Processing for Acrylic Intra Ocular Lens to Prevent Secondary Posterior Capsular Opacification
Author Affiliations & Notes
  • H. Matsushima
    Department of Ophthalmology, Dokkyo University Sch of Med, Shimotsuga–Gun, Japan
  • H. Iwamoto
    HOYA Corporation Medical Division, Saitama, Japan
  • K. Mukai
    Department of Ophthalmology, Dokkyo University Sch of Med, Shimotsuga–Gun, Japan
  • Y. Obara
    Department of Ophthalmology, Dokkyo University Sch of Med, Shimotsuga–Gun, Japan
  • Footnotes
    Commercial Relationships  H. Matsushima, None; H. Iwamoto, HOYA Corporation Medical Division E; K. Mukai, None; Y. Obara, None.
  • Footnotes
    Support  None.
Investigative Ophthalmology & Visual Science May 2005, Vol.46, 2854. doi:https://doi.org/
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    • Get Citation

      H. Matsushima, H. Iwamoto, K. Mukai, Y. Obara; Novel Active Oxygen Processing for Acrylic Intra Ocular Lens to Prevent Secondary Posterior Capsular Opacification . Invest. Ophthalmol. Vis. Sci. 2005;46(13):2854. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract
 
Abstract:
 

Evaluation of active oxygen processing on surface of acrylic intraocular lens to prevent secondary posterior capsular opacification (PCO).

 

Acrylic IOLs were prepared and ultra violet rays were irradiated to active oxygen processing the surface of IOLs. The treated IOLs and control IOLs were prepared for experiments. Eight–week old albino rabbits were anesthetized and phacoemulcification were performed. The treated IOLs were implanted into right eye and the control IOLs were implanted into left eye. After 2 weeks, the rabbits were euthnized and their eye balls were dissected and fixed using 10% formaldehyde. The developed PCOs were observed using light microscopy (DX51, ORIMPUS) after hematoxylin and eosin staining.

 

The thickness of PCO in center was 55 µm using control IOLs; however, it was 15 µm using treated IOLs. Development of PCO was prevented using treated acrylic IOLs by increasing adhesion with posterior capsule.

 

An active oxygen processing on surface of IOLs is novel effective method to prevent secondary PCO after cataract surgery.

 

 

 
Keywords: cataract • clinical laboratory testing • pathology: experimental 
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