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I. Hsu, D. Jardim, B. Soloway, C. Starr; The Rate of Posterior Capsular Opacity With the Crystalens Accommodating IOL . Invest. Ophthalmol. Vis. Sci. 2005;46(13):2857.
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Purpose:This study was designed to calculate the rate of posterior capsular opacification (PCO) with the Crystalens AT–45 Accommodating IOL (Eyeonics, Inc, Aliso Viejo, CA). Methods:A retrospective chart review of 27 consecutive eyes of 25 patients who received the new Crystalens accommodating IOL. A standardized surgical protocol was followed by a single surgeon using phacoemulsification with capsulorhexis (5mm) and a scleral tunnel incision. Follow–up time ranged from one week to 10 months. Results:Forty–four percent (12/27) of patients developed slit–lamp evidence of PCO at a mean postoperative follow–up of 4.9 months. Only 3 of the 27 patients (11%) required a Yag capsulotomy for visually significant PCO at 5 months post–op. Conclusions: Reported pooled rates of PCO with traditional lens implantation in one meta–analysis were 11.8% at 1 year, 20.7% at 3 years, and 28.4% at five years after surgery. This study showed that the rate of clinical PCO with the Crystalens accommodating IOL is 44% with a mean follow–up time of 4.9 months. Even at an earlier postoperative timepoint, the rate of PCO with the Crystalens accommodating IOL appears to be higher than that reported with traditional IOLs.  Schaumberg, DA et al, Ophthalmology 105(7): July 1, 1998, pp. 1213–1221
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