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S. Guo, D.N. Maxwell, R. Wagner, P. DeRespinis; Foveal Hypoplasia in Pediatric Nystagmus– Diagnosis by Optical Coherence Tomography . Invest. Ophthalmol. Vis. Sci. 2005;46(13):2940.
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Purpose: To evaluate the role of Optical Coherence Tomography (OCT) in assessing foveal anatomy in children with nystagmus and to determine if certain types of pediatric nystagmus are associated with characteristic OCT findings. Methods: Potential patients were identified from pediatric clinics using the ICD 9 codes for idiopathic nystagmus, nystagmus associated with albinism, and aniridia. Eight suitable study participants received a complete eye exam, dilated fundoscopy and ocular coherence tomography imaging. Each OCT image was then evaluated separately for abnormalities and compared to other images to determine similarities. Results: Foveal absence and or other abnormailities of foveal anatomy were documented by OCT imaging in approximately 50% of cases. Conclusions: OCT can be used to diagnose foveal hypoplasia in children with nystagmus, and is a helpful tool in assessing foveal abnormalities in this population. However, not all children with nystagmus have anatomical foveal abnormalities that can be documented by OCT. OCT characteristics may predict visual prognosis in both populations.
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