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R. Gangnon, M.D. Davis, L.D. Hubbard, L.M. Aiello, E.Y. Chew, F.L. Ferris, III, Early Treatment Diabetic Retinopathy Study Research Group; A Severity Scale for Diabetic Macular Edema (DME) . Invest. Ophthalmol. Vis. Sci. 2005;46(13):3269.
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To develop a severity scale for DME derived from eyes enrolled in the ETDRS and based on stereo photographic gradings of degree of retinal thickening (RT) at the center of the macula (RT_CM) and area of RT within 1 disc diameter (DD) of center (RT_1DD).
Mean baseline visual acuity (VA) scores were tabulated for eyes cross–classified by RT_CM and RT_1DD. Groups with similar VA scores were combined using cluster analysis and clinical judgment, producing an 8–step scale.
See table below. Mean VA Score at Baseline
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