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A.A. Mokashi, A.D. Singh, J.F. Bena, R. Jacques, P.A. Rundle, I.G. Rennie; Growth of Small Choroidal Melanocytic Lesions . Invest. Ophthalmol. Vis. Sci. 2005;46(13):3393.
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© ARVO (1962-2015); The Authors (2016-present)
To evaluate diagnostic factors that may predict growth of small choroidal melanocytic lesions (SCML).
A cohort of 240 patients with a presumptive diagnosis of SCML was followed prospectively to document growth prior to treatment. Data regarding size, location, diagnostic features, and growth were collected. To evaluate the association between potential risk factors and growth, Barnard’s exact test and Fisher’s exact test were performed for categorical variables and the Wilcoxon Rank Sum test was used for continuous factors.
11 SCML (4.6%) demonstrated growth within 1500 days of follow up. Patients with growth had significantly larger thickness and were significantly closer to the foveola. Significant associations with growth status were observed for gender, symptom, presence of orange pigment, and intrinsic vessels seen with ICG angiogram (Table).
Patients with SCML that demonstrate high risk factors should be followed closely for the initial 4 years as they are likely to represent small melanoma.
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