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K. Sakata, L.M. Sakata, V.M. Sakata, F.A. Litvinsky, C. Santini, G.B. Guedes, S.L. Teixeira, E. Shiokawa, A.T. R. Moreira; The Prevalence of Glaucoma in a Brazilian Population – Projeto Glaucoma Study . Invest. Ophthalmol. Vis. Sci. 2005;46(13):3518.
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Purpose:To determine the prevalence and clinical characteristics of glaucoma in Brazilian subjects older than 40 years. Methods:A cross section epidemiologic study was performed in two districts of Piraquara city, south of Brazil, from June 2000 to December 2003. Each subject was examined according to a standard protocol. The screening evaluation included medical history interview, examination of anterior chamber, applanation tonometry and fundoscopy. All the subjects with a compatible glaucomatous optic disc (CGOD) or IOP above 21 mmHg were selected to return. At this second evaluation, at the Glaucoma sector of our Hospital, a complete ophthalmologic exam was performed, including: visual acuity determination, biomicroscopy, applanation tonometry, gonioscopy, pachimetry, fundoscopy and standard automated perimetry (SAP). All these subjects repeated automated perimetry exam at least once. Definite glaucoma was defined by the presence of a CGOD associated to two abnormal SAP exam, or a cup/disc ratio greater than 0.8 associated to a notch of the neural rim. Results:Of a total of 2139 eligible subjects, 1772 were examined (82.84% overall participation rate). From 226 subjects selected to return, 33 did not returned (14.60%). It was observed a 3.95% (95% confidence interval, 3.04% – 4.86%) prevalence of glaucoma (70 subjects). From the 70 glaucoma subjects, there were 25 (35.72%) patients with primary open angle glaucoma (POAG); 29 (41.43%) patients with normal tension glaucoma (NTG); 11 (15.71%) patients with angle closure glaucoma (ACG) and 5 (7.14%) patients with secondary glaucoma. Eleven (15.71%) of the glaucoma patients have at least one eye considered legally blind from glaucoma (6 POAG; 1 ACG; 4 secondary glaucoma).Seventeen subjects had CGOD but did not achieve the criteria for glaucoma diagnosis and were classified as possible glaucomatous patients. Conclusions:The prevalence of glaucoma in a Brazilian population was higher than reported for Hispanic population. At diagnosis, 15% of the glaucomatous patients were blind from at least one eye.
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