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P. Taravati, C.F. Brito, K.R. Woodward, C.K. Doyle, R.H. Kardon, M. Wall; The Effect of Stimulus Size on Perimetric Variability . Invest. Ophthalmol. Vis. Sci. 2005;46(13):3718.
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to evaluate the effect of stimulus size on variability of four automated perimetry methods in glaucoma patients.
We tested 6 glaucoma patients with SITA MD range: –0.66 to –15.2 dB and average: –8.4 ± 4.37.once a week for 5 weeks. We tested patients in random order using four perimetry tests: 1) Humphrey program 24–2 size III, 2) Humphrey program 24–2 size V, 3) Humphrey Matrix and 4) motion perimetry.
There was a clear rise in variability associated with lower visual field sensitivity when stimulus size was fixed using Goldmann size III and size V stimuli with Humphrey automated perimetry. Variability remained relatively constant across visual field sensitivities with the large fixed–size stimuli of the Humphrey Matrix and with motion perimetry (a method that measures threshold by changing stimulus size until the smallest size stimulus can be detected by a subject in each visual field location). After eliminating the values subject to a floor effect, we found the following correlations:
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