Comparing the Ability of Visual Field Testing by Matrix Perimetry and Swedish Interactive Thresholding Algorithm (SITA) Perimetry to Detect Glaucoma

Abstract

 

Abstract:

 

Matrix perimetry (Carl Zeiss Meditec, Inc., Dublin, CA) is a new iteration of frequency doubling technology (FDT) using 24–2 stimulus presentation pattern. This study compared Matrix perimetry and SITA perimetry ability to detect glaucoma.

 

One eye of 61 consecutive patients evaluated in the glaucoma clinic at UPMC Eye Center as well as 9 healthy volunteers were included in this study. All subjects underwent optic nerve head (ONH) photography, SITA and Matrix perimetry and optical coherence tomography (OCT) within 6 months interval. Mean deviation (MD), pattern standard deviation (PSD) and glaucoma hemifield test (GHT) were recorded for each perimetry device. The ONH photographs were evaluated by 3 glaucoma experts in an independent masked fashion. Glaucoma diagnosis was established by either glaucomatous optic neuropathy (GON) or OCT retinal nerve fiber layer (RNFL) average below the first percentile using the StratusOCT normative database. Quantitative evaluation was established by average vertical cup to disc (CD) ratio assessed from ONH photographs by 3 glaucoma experts, as well as by OCT mean RNFL thickness.

 

The sensitivity and specificity of the GHT as well as the area under the receiver operating characteristic curve (AROC) of MD and PSD for both perimetry devices for discriminating between healthy and glaucomatous eyes are shown in the table below. There was no statistically significant difference (p>0.05) between any corresponding Matrix and SITA analysis results. There was no significant difference between the correlations of Matrix and SITA MD and PSD with either vertical CD ratio or OCT mean RNFL.

 

 

^{There was no significant difference in the discriminating ability of Matrix and SITA VF for GHT, MD and PSD regardless of whether the diagnosis was established by ONH assessment or OCT}

 

 

Keywords: perimetry • optic disc • imaging/image analysis: clinical