May 2005
Volume 46, Issue 13
ARVO Annual Meeting Abstract  |   May 2005
Peripapillary Microperimetry in Glaucomatous Eyes
Author Affiliations & Notes
  • M. Dorigo
    Ophthalmology, University of Padova, Padova, Italy
  • E. Midena
    Ophthalmology, University of Padova, Padova, Italy
    Fondazione GB Bietti per l'Oftalmologia, Roma, Italy
  • V. Maritan
    Ophthalmology, University of Padova, Padova, Italy
  • E. Convento
    Ophthalmology, University of Padova, Padova, Italy
  • Footnotes
    Commercial Relationships  M. Dorigo, None; E. Midena, None; V. Maritan, None; E. Convento, None.
  • Footnotes
    Support  None.
Investigative Ophthalmology & Visual Science May 2005, Vol.46, 3735. doi:
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    • Get Citation

      M. Dorigo, E. Midena, V. Maritan, E. Convento; Peripapillary Microperimetry in Glaucomatous Eyes . Invest. Ophthalmol. Vis. Sci. 2005;46(13):3735.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract: : Purpose: To determine, in patients with ocular hypertension and glaucoma, the existence of peripapillary threshold reduction using microperimetry and to evaluate the association between peripapillary sensitivity and retinal nerve fiber layer (RNFL) thickness. Methods: Fourteen eyes affected by ocular hypertension, ninteen eyes affected by glaucoma and fourteen age–matched controls underwent: peripapillary sensitivity quantification with microperimetry (fundus–related microperimetry; MP1 Microperimeter, Nidek Technologies, Padova, Italy) using a standardized peripapillary grid. RNFL thickness was quantified, using optical coherence tomography (Stratus OCT, Carl Zeiss, Jena, Germany), in a ring exactly corresponding to microperimetry threshold quantification. Standard automatic perimetry was performed in all except control eyes. Results: Peripapillary threshold was 17.1 ± 4.1, 13.4 ± 6.7 and 8.9 ± 6.6 db in control, ocular hypertension and glaucomatous eyes respectively (p < .0001). Progressive significant (p<.001) reduction of RNFL thickness was documented in ocular hypertension and glaucomatous eyes compared to controls. Significant correlation (r= 0.75) was documented just in control and ocular hypertension eyes between RNFL thickness and corresponding peripapillary sensitivity. Individual patterns of sensiivity vs RNFL thickness were identified in the examined groups. Conclusions: Microperimetric exact quantification of peripapillary sensitivity may be used as a new functional parameter in the integrated morpho–functional evaluation of glaucomatous eyes.

Keywords: imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) • nerve fiber layer • perimetry 

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