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B. Ejdervik Lindblad, N. Håkansson, B. Philipson, A. Wolk; A Prospective Study of Body Mass Index and Risk of Cataract Extraction in Women . Invest. Ophthalmol. Vis. Sci. 2005;46(13):3837.
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Purpose: To investigate the association between body mass index (BMI, defined by weight in kilograms divided by square of height in meters) and cataract extraction in women Methods: We examined the association between body mass index and cataract extraction in a population based cohort of 34,623 women. Detailed information about diet and life–style factors was obtained through a self–administered questionnaire. During follow–up between September 1997 and June 2002, 2128 women had a cataract extraction. Analysis was performed using Cox proportional hazard models. Results: Women with overweight (BMI 25.0–29.9) or obesity (BMI≥30) had a relative risk of 0.94 (95% CI 0.86–1.04) and 1.04 (95% CI 0.90–1.20), respectively for cataract extraction, compared to women with normal weight (BMI 18.5–24.9). Adjustment was made for possible confounders (age, smoking, alcohol consumption, hypertension, diabetes, steroid medication, education, and antioxidant supplementation). The relative risk for women with underweight (BMI< 18.5) was not significantly increased (RR 1.15; 95% CI 0.89–1.49). When we excluded women with diabetes the risk estimates were fairly unchanged. Conclusions: Overweight or obesity among women is not associated with increased risk of cataract extraction.
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