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N. Horio, A. Tanikawa, T. Mizuguchi, M. Horiguchi; Radial Optic Neurotomy Does Not Improve Retinal Blood Flow in Eyes With Central Retinal Vein Occlusion . Invest. Ophthalmol. Vis. Sci. 2005;46(13):4028.
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© ARVO (1962-2015); The Authors (2016-present)
Purpose: To determine the effect of redial optic neurotomy (RON) on retinal blood flow (RBF) in eyes with central retinal vein occlusion (CRVO). Methods: Seven eyes of 7 patients with CRVO underwent RON and vitrectomy, and were prospectively followed for more than 6 months. Using video fluorescein angiography, retinal blood flow (RBF) was calculated with mean circulation time, artery diameter, and vein diameter. Foveal thickness (FT) was measured using optical coherent tomography. Indocyanine green angiography (IA) was applied to detect chorioretinal anastomoses. Results: Preoperatively, the RBF in the affected eye (28.5 ± 5.4 pixel 2 /sec) was significantly lower than that in the healthy fellow eye (39.9 ± 8.7 pixel 2 /sec) ( P = 0.01). At 1 week after surgery, the RBF was significantly attenuated to 21.1 ± 6.6 pixel 2 /sec ( P < 0.01), while the FT was decreased from 711 ± 271 to 499 ± 212 µm. IA showed chorioretinal anasitomoses in all 7 eyes at 6 months after surgery. However, the RBF at 6 months (26.0 ± 7.7 pixel 2 /sec) was not different from the preoperative RBF. The FT at 6 months was significantly decreased to 488 ± 182 µm compared with the preoperative FT ( P = 0.03). Conclusions: Our data demonstrating no beneficial effect of RON on RBF but improvement of macular edema indicates that vitrectomy may play an important role. The chorioretinal anastomoses may not improve the RBF to the normal level.
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