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T. Aggermann, C. Glittenberg, A. Abri, S. Binder; Evaluation of Radial Optic Neurotomy for Central Retinal Vein Occlusion by Optical Coherence Tomography and Multifocal Electroretinography : . Invest. Ophthalmol. Vis. Sci. 2005;46(13):4033.
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© ARVO (1962-2015); The Authors (2016-present)
Purpose: To evaluate the postoperative outcome after radial optic neurotomy (RON) in patients with central retinal vein occlusion (CRVO) using multifocal electroretinography (m–ERG) and optical coherence tomography (OCT). Methods: After the informed consent, RON was performed in 14 eyes of 14 patients with perfused and non perfused CRVO. OCT was used to measure maximal foveal thickness. The m–ERG was used to provide an objective method of evaluating central retina function, and to provide functional information on a larger area of the macula than can be obtained from visual acuity in low vision patients. Examinations were performed pre– and postoperatively, after one month and then every three months thereafter. Results: Mean follow up time was 12 months; average patient age was 64 years. 57% of CRVO cases were perfused, 43% were non perfused. OCT: The OCT showed a significant reduction of macula thickness from a mean preoperative maximal foveal thickness of 801µm to 432µm at the last examination (p=0,001). m–ERG: The b–wave amplitudes were significantly increased after RON from preoperative 67.2 nV/deg², to values of 93.3 nV/deg² at last examination(p=0,027). The a–wave amplitudes showed no significant change from preoperative values of 54.6 nV/deg², to values of 53.5 nV/deg² at last examination. Conclusions: Our results suggest that RON might become an efficient therapeutic option in eyes with CRVO. In our study the OCT showed a significant reduction of macula edema. In most of our patients the b–wave amplitude in the m–ERG increased significantly without an accompanying increase of the a–wave, suggesting a predominantly inner retinal functional recovery.
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