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J.C. Chen, I.J. Galic; The Effectiveness of Triamcinolone Acetate Intravitreal Injection in Retinal Vascular Diseases . Invest. Ophthalmol. Vis. Sci. 2005;46(13):4046.
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© ARVO (1962-2015); The Authors (2016-present)
Purpose:To evaluate the effectiveness of intravitreal triamcinolone for the treatment of macular edema associated with different retinal vascular conditions. Methods:A retrospective chart review of patients presenting with macular edema who have been treated with intravitreal triamcinolone over a two–year period. Pre–treatment and post–treatment visual acuity, optical coherence tomography (OCT) findings, fluorescein angiogram and intraocular pressure were analyzed. Results: 160 patients were reviewed. 89 patients were included in the study and had the following diagnoses; diabetic retinopathy, central vein occlusion, branch vein occlusion and post–operative cystoid macular edema (CME). Visual improvement was seen in 52% of patients had visual acuity improvement (diabetic retinopathy 51%, central vein occlusion 42%, branch vein occlusion 50%, post–operative CME 55%). Anatomic improvement, as documented by OCT, occurred in the majority regardless of functional outcome. Effectiveness of treatment decreases with chronicity of disease. Complications included elevated intraocular pressure in 47% of patients. No endophthalmitis was encountered in this group. Conclusions: Intravitreal triamcinolone is an effective treatment for macular edema of various causes. Early intervention prior to structural damage is recommended.
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