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K. Yata, N. Horio, A. Tanikawa, M. Horiguchi; Intraoperative Video Fluorescein Angiography Using Optical Fiber–Free Intravtreal Surgery System for Retinal Blood Flow Analysis . Invest. Ophthalmol. Vis. Sci. 2005;46(13):4047.
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© ARVO (1962-2015); The Authors (2016-present)
Purpose:To report a new method to perform intraoperative video fluorescein angiography (VFA) using an optical fiber–free intravitreal surgery system (OFFISS) and retinal blood flow analysis during surgery. Methods:Four eyes of 4 patients with macular edema secondary to branch retinal vein occlusion underwent vitrectomy and intraoperative VFA with a bolus of 0.8 ml fluorescein dye. The mean circulation time (MCT) and segmental blood flow (SBF) were calculated using dye dilution technique. Intraocular pressure was maintained at 15 mmHg. Results:The VFA was clearly recorded with stable excitation light and very little eye movement under retrobulbar anesthesia. The MCT of the affected vessels (6.11 ± 2.21 seconds) was significantly longer than that of the healthy vessels (1.70 ± 0.70 seconds) (P < 0.05). The SBF of the affected vessels (6.1 ± 1.2 pixel2/sec) was significantly lower than that of the healthy vessels (17.9 ± 7.9 pixel2/sec) (P < 0.05). Conclusions:The combination of VFA and OFFISS can facilitate intraoperative VFA, and may be useful for evaluating retinal blood flow during surgery.
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