High Speed ICG Evaluation of Central Serous Retinopathy

Abstract

Abstract: : Purpose: Hot spots on static ICG images have been described in patients with active central serous retinopathy (CSR). This study describes the findings of high speed ICG imaging in patients with active CSR.Methods: A retrospective case study was conducted on patients with active CSR undergoing ETDRS visual acuity, fluorescein angiography, OCT, static and high speed ICG imaging. Cases were defined by the presence of a dilated choroidal venule present on the high speed ICG at the site of fluorescein leakage. Control patients were defined as patients with active CSR but no dilation of choroidal venules at the leakage site. Cases and controls were analyzed to determine discriminating features.Results: 32 eyes of 30 patients were reviewed. 17 eyes were noted to have choroidal vascular dilation at the site of fluorescein angiographic leakage. There was no significant difference in presenting visual acuity between the 2 groups. Pigment epithelial detachments noted on OCT were more frequent in case patients with dilated choroidal venules ( 47 % vs 24 % ). Final visual acuity outcomes were similar in the 2 groups.Conclusions: speed ICG may demonstrate localized areas of choroidal vascular dilation at the site of fluorecein leakage in some cases of CSR. Patients with dilated choroidal vessels appear to be more likely to have a pigment epithelial detachment on OCT. High speed ICG suggests a hemodynamic pathogenesis for CSR in some patients.

Keywords: macula/fovea • imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) • imaging/image analysis: clinical