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M. Kuze, H. Matsubara, M. Sasoh, Y. Uji; Evaluation of Idiopathic Juxtafoveolar Teleangiectasia by Multifocal Electroretinography . Invest. Ophthalmol. Vis. Sci. 2005;46(13):4067.
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© ARVO (1962-2015); The Authors (2016-present)
Purpose: To evaluate the changes of retinal function in patients with idiopathic juxtafoveolar retinal teleangiectasis (IJT). Patients and methods: Seven eyes of six patients with IJT (M:W/2:4, mean age 55.4 years) underwent detailed ophthalmologic evaluation including fundus photography, fluorescein angiography (FA), full–field ERGs, and multifocal ERGs (mfERGs). The mfERGs were grouped and analyzed by concentric rings. Results from the affected eyes were compared to those from the fellow eyes. Results:All affected eyes showed a slow increase of fluorescein leakage during the follow–up period. Topographical examination of the mfERG showed a more significant reduction in amplitude and delay in latencies in areas beyond that of the angiographic changes (P <0.05). An improvement of the fundus appearance was detected by FA, but was not correlated with the improvement of visual acuity or by an increase in the amplitude or shortening in the latency of the mfERGs. Obvious abnormalities of the full–field ERGs were not detected in the 4 unilateral cases. The one bilateral case showed a gradual decrease of visual acuity accompanied by a decrease in the amplitude and increased latency of P1 of the mfERG in both eyes. Conclusions: The results from the mfERGs demonstrated a depression of the function in the perifoveal region with angiographic changes of IJT, whereas full–field ERG did not. The function of retinal neural cells in patients with IJT deteriorates even in the areas without any retinal lesion. mfERG is a sensitive method for delineating the subclinical retinal areas and changes in IJT.
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