Abstract
Abstract: :
Purpose: To describe the indocyanine green (ICG) angiographic characteristics of two patients with Sorsby’s fundus dystrophy at both ends of the clinical spectrum of this disorder. Methods: Case presentations Results: In one patient the ICG angiography revealed late–staining plaques not seen on the fluorescein angiography. The patient subsequently developed choroidal neovascularization in the same area. In the other patient with progressive choroidal neovascularization and scarring the ICG angiography showed an area of hypofluorescence corresponding to the scar and a well–defined staining plaque larger than the area of neovascularization suggested clinically. Conclusions: It is questionable whether the ICG staining plaques are the source of the neovascularization. However, it is clear from our patients that the chorioretinal disease in Sorsby’s patients is more widespread than suggested either by the clinical exam or by the fluorescein angiography. ICG angiography may have a predictive value in determining prognosis and response to treatment in this condition.
Keywords: retinal degenerations: hereditary • choroid: neovascularization • imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound)