Purchase this article with an account.
J.A. Urrets–Zavalia, J. Venturino, J.E. Mercado, J. Saad, E.A. Urrets–Zavalia; Optical Coherence Tomography Imaging of the Macula in X–Linked Juvenile Retinoschisis . Invest. Ophthalmol. Vis. Sci. 2005;46(13):4085.
Download citation file:
© ARVO (1962-2015); The Authors (2016-present)
Purpose: To present Optical Coherence Tomography (OCT) findings in the evaluation of the macula satus in X–linked retinoschisis (XLRS). Materials and Methods: Two brothers 20 and 25 years old with XLRS were evaluated with the Straus 3.0 OCT (Carl Zeiss Meditec AG, Jena, Germany). Qualitative and quantitative analysis of the macula was performed from six radial scans centered on the fovea. Vertical or oblique scans were also obtained from outside the inferior temporal vascular arcade. Results: Macular clivage was clearly observed at the level of the retinal outer plexiform layer (ROPL). In addition, discrete isolated macular schisis appeared under the retinal nerve fiber layer (RNFL) in some areas, as well as areas of RNFL loss or detachment outside the inferior temporal vascular arcade. Macular elevation and schisis, and the presence of oblique or vertical thin–wall structures separating intraretinal cavities was pronounced and characteristic. Macular dark spaces were interpreted as intraretinal cavities with a thin internal and an irregular external neuroretinal layer, decreasing rapidly in size from the center towards the macular periphery. OCT showed mild differences in the cavitation pattern between these two patients, and moderate asymmetry between both eyes in a same patient. The macular thickness and elevation was more pronounced in the younger patient (mean thickness in both eyes= 543 µ in the younger vs 305 µ in the older patient). OCT did not show abnormal vitreomacular relationship or traction over the macular area. Conclusions: OCT shows a characteristic pattern of macular schisis and cavitation in XLRS. Macular retinoschisis occurs principally at the ROPL. Outside the posterior pole retinoschisis seems to affect the RNFL. Macular thickness may decrease with age and no posterior vitreous cortex traction over the macular area was apparently involved in the foveal splitting and elevation.
This PDF is available to Subscribers Only