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Y. Minami, S. Ishiko, Y. Takai, Y. Kato, H. Kagokawa, A. Takamiya, J. Takahashi, T. Nagaoka, R. Kinouchi, A. Yoshida; Retinal Changes in Juvenile X–Linked Retinoschisis Using 3–Dimentional Optical Coherence Tomography . Invest. Ophthalmol. Vis. Sci. 2005;46(13):4087.
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© ARVO (1962-2015); The Authors (2016-present)
Purpose: To report the retinal changes in juvenile X–linked retinoschisis using 3–dimentional optical coherence tomography (3–D OCT). Methods: 3–D OCT performed on a 7–year–old boy with X–linked retinoschisis. 3–D OCT uses the transverse scanning strategy of the scanning laser ophthalmoscope (SLO) (C–scan) and the interferometric signal processing of the OCT (B–scan) and produces simultaneous, paired images that show the retinal surface details and progressively deeper slides of the subsurface anatomy. Results: Funduscopy showed a silver–gray retinal reflex and cartwheel–like macular degeneration in both eyes. Peripheral retinoschisis was absent. 3–D OCT C–scan showed the extent of the split retina and cystoid spaces. 3–D OCT B–scan showed that the retina was split into two layers in the central fovea that was thought to be at the outer plexiform layer. In the parafoveal retina, the retina was split into four layers and thought to occur at the nerve fiver layer or ganglion cell layer, the outer plexiform layer, and the outer nuclear layer. Conclusions: We for the first timedemonstrated that schisis can occur in any retinal layers in X–linked retinoschisis in living eye. 3–D OCT would be useful to evaluate the retinal pathology and follow patients non–invasively.
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